Access to high quality, comprehensive clinical information is essential for meeting research and operational analytical needs at Dana-Farber. The Hematologic Malignancy Data Repository (HMDR) is an inter-departmental effort aimed at meeting the specific challenges of conducting research on hematologic malignancies. The HMDR team provides support for the entire research pipeline: from hypothesis generation and study design, to obtaining regulatory approval and facilitating data access. Our goal is to reduce the gap between asking a question and analyzing data.